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GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth
We report here the identification of GIDE, a mitochondrially located E3 ubiquitin ligase. GIDE contains a C-terminal Ring finger domain, which is mostly conserved with those of the IAP family members, and which is required for its E3 ligase activity. Overexpression of GIDE induces apoptosis via a pa...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156110/ https://ncbi.nlm.nih.gov/pubmed/18591963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2008.75 |
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