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Preparation of Oligomeric β-amyloid(1-42) and Induction of Synaptic Plasticity Impairment on Hippocampal Slices
Impairment of synaptic connections is likely to underlie the subtle amnesic changes occurring at the early stages of Alzheimer s Disease (AD). β-amyloid (Aβ), a peptide produced in high amounts in AD, is known to reduce Long-Term Potentiation (LTP), a cellular correlate of learning and memory. Indee...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
MyJove Corporation
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156071/ https://ncbi.nlm.nih.gov/pubmed/20644518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/1884 |
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