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A conserved archaeal pathway for tail-anchored membrane protein insertion
Eukaryotic tail-anchored (TA) membrane proteins are inserted into the endoplasmic reticulum by a post-translational TRC40 pathway, but no comparable pathway is known in other domains of life. The crystal structure of an archaebacterial TRC40 sequence homolog bound to ADP•AlF(4)(−) reveals characteri...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155638/ https://ncbi.nlm.nih.gov/pubmed/21658170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2011.01229.x |
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