Split T Cell Tolerance against a Self/Tumor Antigen: Spontaneous CD4(+) but Not CD8(+) T Cell Responses against p53 in Cancer Patients and Healthy Donors

Analyses of NY-ESO-1-specific spontaneous immune responses in cancer patients revealed that antibody and both CD4(+) and CD8(+) T cell responses were induced together in cancer patients. To explore whether such integrated immune responses are also spontaneously induced for other tumor antigens, we h...

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Detalhes bibliográficos
Main Authors: Tsuji, Takemasa, Matsuzaki, Junko, Ritter, Erika, Miliotto, Anthony, Ritter, Gerd, Odunsi, Kunle, Old, Lloyd J., Gnjatic, Sacha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155555/
https://ncbi.nlm.nih.gov/pubmed/21858191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023651
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