Molecular Interaction of TPPP with PrP Antagonized the CytoPrP-Induced Disruption of Microtubule Structures and Cytotoxicity

BACKGROUND: Tubulin polymerization promoting protein/p25 (TPPP/p25), known as a microtubule-associated protein (MAP), is a brain-specific unstructured protein with a physiological function of stabilizing cellular microtubular ultrastructures. Whether TPPP involves in the normal functions of PrP or t...

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Autors principals: Zhou, Rui-Min, Jing, Yuan-Yuan, Guo, Yan, Gao, Chen, Zhang, Bao-Yun, Chen, Cao, Shi, Qi, Tian, Chan, Wang, Zhao-Yun, Gong, Han-Shi, Han, Jun, Xu, Bian-Li, Dong, Xiao-Ping
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155546/
https://ncbi.nlm.nih.gov/pubmed/21857997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023079
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