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Functional Studies on Twenty Novel Naturally Occurring Melanocortin-4 Receptor Mutations
The melanocortin-4 receptor (MC4R) is a G protein-coupled receptor critically involved in regulating energy balance. MC4R activation results in decreased food intake and increased energy expenditure. Genetic and pharmacological studies demonstrated that the MC4R regulation of energy balance is conse...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155388/ https://ncbi.nlm.nih.gov/pubmed/21729752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2011.06.008 |
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