Identification and Functional Characterization of Novel Mutations in the Melanocortin-4 Receptor

OBJECTIVE: Melanocortin-4 receptor (MC4R) deficiency is the most common cause of monogenic obesity. In the present study, we screened the MC4R gene for mutations in a population of overweight and obese children and adolescents. METHOD: Cross-sectional mutation analysis of 112 overweight/obese childr...

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Detalhes bibliográficos
Publicado no:Obes Facts
Main Authors: Beckers, Sigri, Zegers, Doreen, de Freitas, Fenna, Peeters, Armand V., Verhulst, Stijn L., Massa, Guy, Van Gaal, Luc F., Timmermans, Jean-Pierre, Desager, Kristine N., Van Hul, Wim
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452105/
https://ncbi.nlm.nih.gov/pubmed/20975296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000321565
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