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The Melanocortin-4 Receptor: Physiology, Pharmacology, and Pathophysiology
The melanocortin-4 receptor (MC4R) was cloned in 1993 by degenerate PCR; however, its function was unknown. Subsequent studies suggest that the MC4R might be involved in regulating energy homeostasis. This hypothesis was confirmed in 1997 by a series of seminal studies in mice. In 1998, human geneti...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365848/ https://ncbi.nlm.nih.gov/pubmed/20190196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2009-0037 |
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