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Functional Characterization of Nine Novel Naturally Occurring Human Melanocortin-3 Receptor Mutations

The melanocortin-3 receptor (MC3R) is a member of family A rhodopsin-like G protein-coupled receptor. Mouse genetic studies suggested that MC3R and the related MC4R are non-redundant regulators of energy homeostasis. Lack of Mc3r leads to higher feed efficiency and fat mass. However, until now only...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Yang, Fan, Tao, Ya-Xiong
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465685/
https://ncbi.nlm.nih.gov/pubmed/22884546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.07.017
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