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Functional Characterization of Nine Novel Naturally Occurring Human Melanocortin-3 Receptor Mutations
The melanocortin-3 receptor (MC3R) is a member of family A rhodopsin-like G protein-coupled receptor. Mouse genetic studies suggested that MC3R and the related MC4R are non-redundant regulators of energy homeostasis. Lack of Mc3r leads to higher feed efficiency and fat mass. However, until now only...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465685/ https://ncbi.nlm.nih.gov/pubmed/22884546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.07.017 |
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