SCF(FBXL15) regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1

Smad ubiquitination regulatory factor 1 (Smurf1), an homologous to E6AP C-terminus (HECT)-type E3 ubiquitin ligase, performs a crucial role in the regulation of the bone morphogenetic protein (BMP) signalling pathway in both embryonic development and bone remodelling. How the stability and activity...

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Autors principals: Cui, Yu, He, Shan, Xing, Cencan, Lu, Kefeng, Wang, Jian, Xing, Guichun, Meng, Anming, Jia, Shunji, He, Fuchu, Zhang, Lingqiang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155294/
https://ncbi.nlm.nih.gov/pubmed/21572392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.155
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