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Huntington’s Disease: From Mutant Huntingtin Protein to Neurotrophic Factor Therapy
Huntington’s disease (HD) is an inherited disorder characterized by neuronal dysfunction and degeneration in striatum and cerebral cortex. Although the signaling pathways involved in HD are not yet clearly elucidated, mutant huntingtin protein is a key factor in the induction of neurodegeneration. T...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Master Publishing Group
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154262/ https://ncbi.nlm.nih.gov/pubmed/21841917 |
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