A carregar...

Genistein induces degradation of mutant huntingtin in fibroblasts from Huntington’s disease patients

Mutations in the HTT gene, consisting of expansion of CAG triplets, cause the Huntington’s disease (HD), one of the major neurodegenerative disorders. Formation of aggregates of mutant huntingtin (mHTT, the product of the mutant HTT gene) leads to cellular dysfunctions, and subsequent neurodegenerat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Metab Brain Dis
Main Authors: Pierzynowska, Karolina, Gaffke, Lidia, Cyske, Zuzanna, Węgrzyn, Grzegorz
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520327/
https://ncbi.nlm.nih.gov/pubmed/30850940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-019-00405-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!