Proteasome Composition and Activity Changes in Cultured Fibroblasts Derived From Mucopolysaccharidoses Patients and Their Modulation by Genistein

In this study, we have asked whether proteasome composition and function are affected in cells derived from patients suffering from all types of mucopolysaccharidosis (MPS), an inherited metabolic disease caused by accumulation of undegraded glycosaminoglycans (GAGs). Moreover, we have tested if gen...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Pierzynowska, Karolina, Gaffke, Lidia, Jankowska, Elżbieta, Rintz, Estera, Witkowska, Julia, Wieczerzak, Ewa, Podlacha, Magdalena, Węgrzyn, Grzegorz
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606483/
https://ncbi.nlm.nih.gov/pubmed/33195185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.540726
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