Proteasome Composition and Activity Changes in Cultured Fibroblasts Derived From Mucopolysaccharidoses Patients and Their Modulation by Genistein

In this study, we have asked whether proteasome composition and function are affected in cells derived from patients suffering from all types of mucopolysaccharidosis (MPS), an inherited metabolic disease caused by accumulation of undegraded glycosaminoglycans (GAGs). Moreover, we have tested if gen...

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Dades bibliogràfiques
Publicat a:Front Cell Dev Biol
Autors principals: Pierzynowska, Karolina, Gaffke, Lidia, Jankowska, Elżbieta, Rintz, Estera, Witkowska, Julia, Wieczerzak, Ewa, Podlacha, Magdalena, Węgrzyn, Grzegorz
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606483/
https://ncbi.nlm.nih.gov/pubmed/33195185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.540726
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