Proteasome Composition and Activity Changes in Cultured Fibroblasts Derived From Mucopolysaccharidoses Patients and Their Modulation by Genistein

In this study, we have asked whether proteasome composition and function are affected in cells derived from patients suffering from all types of mucopolysaccharidosis (MPS), an inherited metabolic disease caused by accumulation of undegraded glycosaminoglycans (GAGs). Moreover, we have tested if gen...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Cell Dev Biol
Päätekijät: Pierzynowska, Karolina, Gaffke, Lidia, Jankowska, Elżbieta, Rintz, Estera, Witkowska, Julia, Wieczerzak, Ewa, Podlacha, Magdalena, Węgrzyn, Grzegorz
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2020
Aiheet:
Cell and Developmental Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606483/
https://ncbi.nlm.nih.gov/pubmed/33195185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.540726
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