Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes

The mammalian heart loses its regenerative potential soon after birth. Adult cardiac myocytes (ACMs) permanently exit the cell cycle, and E2F-dependent genes are stably silenced, although the underlying mechanism is unclear. Heterochromatin, which silences genes in many biological contexts, accumula...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Sdek, Patima, Zhao, Peng, Wang, Yaping, Huang, Chang-jiang, Ko, Christopher Y., Butler, Peter C., Weiss, James N., MacLellan, W. Robb
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2011
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153646/
https://ncbi.nlm.nih.gov/pubmed/21825075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201012049
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki