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Repressive Histone Methylation Regulates Cardiac Myocyte Cell Cycle Exit

Mammalian cardiac myocytes (CMs) stop proliferating soon after birth and subsequent heart growth comes from hypertrophy, limiting the adult heart’s regenerative potential after injury. The molecular events that mediate CM cell cycle exit are poorly understood. To determine the epigenetic mechanisms...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: El-Nachef, Danny, Oyama, Kyohei, Wu, Yun-Yu, Freeman, Miles, Zhang, Yiqiang, MacLellan, W. Robb
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542357/
https://ncbi.nlm.nih.gov/pubmed/29800554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.05.013
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