Kinetic Analysis of Substrate Utilization by Native and TNAP-, NPP1-, or PHOSPHO1-Deficient Matrix Vesicles

During the process of endochondral bone formation, chondrocytes and osteoblasts mineralize their extracellular matrix by promoting the formation of hydroxyapatite seed crystals in the sheltered interior of membrane-limited matrix vesicles (MVs). Here, we have studied phosphosubstrate catalysis by os...

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Библиографические подробности
Главные авторы: Ciancaglini, Pietro, Yadav, Manisha C, Simão, Ana Maria Sper, Narisawa, Sonoko, Pizauro, João Martins, Farquharson, Colin, Hoylaerts, Marc F, Millán, José Luis
Формат: Artigo
Язык:Inglês
Опубликовано: Wiley Subscription Services, Inc., A Wiley Company 2010
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153326/
https://ncbi.nlm.nih.gov/pubmed/19874193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/jbmr.091023
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