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Kinetic Analysis of Substrate Utilization by Native and TNAP-, NPP1-, or PHOSPHO1-Deficient Matrix Vesicles
During the process of endochondral bone formation, chondrocytes and osteoblasts mineralize their extracellular matrix by promoting the formation of hydroxyapatite seed crystals in the sheltered interior of membrane-limited matrix vesicles (MVs). Here, we have studied phosphosubstrate catalysis by os...
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Κύριοι συγγραφείς: | , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3153326/ https://ncbi.nlm.nih.gov/pubmed/19874193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/jbmr.091023 |
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