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IKKβ Activation Is Sufficient for RANK-Independent Osteoclast Differentiation and Osteolysis

Monocytes differentiate into osteoclasts through stimulation of receptor activator of NF-κB (RANK). Many downstream effectors of RANK play a positive role in osteoclastogenesis, but their relative importance in osteoclast differentiation is unclear. We report the discovery that activation of a singl...

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Detalhes bibliográficos
Main Authors: Otero, Jesse E, Dai, Simon, Alhawagri, Muhammad A, Darwech, Isra, Abu-Amer, Yousef
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153134/
https://ncbi.nlm.nih.gov/pubmed/20200955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.4
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