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CD28 Expressed on Malignant Plasma Cells Induces A Pro-Survival and Immunosuppressive Microenvironment

Interactions between the malignant plasma cells of multiple myeloma (MM) and stromal cells within the bone marrow (BM) microenvironment are essential for myeloma cell survival, mirroring the same dependence of normal BM-resident long-lived plasma cells on specific marrow niches. These interactions d...

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Autors principals: Nair, Jayakumar R., Carlson, Louise M., Koorella, Chandana, Rozanski, Cheryl H., Byrne, Gerald E., Bergsagel, P. Leif, Shaughnessy, John P., Boise, Lawrence H., Chanan-Khan, Asher, Lee, Kelvin P.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152989/
https://ncbi.nlm.nih.gov/pubmed/21715687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100016
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