CD28-mediated pro-survival signaling induces chemotherapeutic resistance in multiple myeloma

Chemotherapeutic resistance remains a significant hurdle in the treatment of multiple myeloma (MM) and is significantly mediated by interactions between MM cells and stromal cells of the bone marrow microenvironment. Despite the importance of these interactions, the specific molecules and downstream...

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Detalhes bibliográficos
Main Authors: Murray, Megan E., Gavile, Catherine M., Nair, Jayakumar R., Koorella, Chandana, Carlson, Louise M., Buac, Daniela, Utley, Adam, Chesi, Marta, Bergsagel, P. Leif, Boise, Lawrence H., Lee, Kelvin P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055924/
https://ncbi.nlm.nih.gov/pubmed/24782505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-530964
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