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Functionally biased modulation of A(3) adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers

Allosteric modulators for the G(i)-coupled A(3) adenosine receptor (AR) are of considerable interest as therapeutic agents and as pharmacological tools to probe various signaling pathways. In this study, we initially characterized the effects of several imidazoquinolinamine allosteric modulators (LU...

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Autors principals: Gao, Zhan-Guo, Verzijl, Dennis, Zweemer, Annelien, Ye, Kai, Göblyös, Anikó, IJzerman, Adriaan P., Jacobson, Kenneth A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152598/
https://ncbi.nlm.nih.gov/pubmed/21718691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.06.017
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