Toll-like receptor 7 (TLR7)–driven accumulation of a novel CD11c(+) B-cell population is important for the development of autoimmunity

Females are more susceptible than males to many autoimmune diseases. The processes causing this phenomenon are incompletely understood. Here, we demonstrate that aged female mice acquire a previously uncharacterized population of B cells that we call age-associated B cells (ABCs) and that these cell...

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Bibliografski detalji
Glavni autori: Rubtsov, Anatoly V., Rubtsova, Kira, Fischer, Aryeh, Meehan, Richard T., Gillis, Joann Z., Kappler, John W., Marrack, Philippa
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2011
Teme:
Immunobiology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152497/
https://ncbi.nlm.nih.gov/pubmed/21543762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-01-331462
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