Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death

Granzyme-mediated cell death is the major pathway for cytotoxic lymphocytes to kill virus-infected and tumor cells. In humans, five different granzymes (i.e. GrA, GrB, GrH, GrK, and GrM) are known that all induce cell death. Expression of intracellular serine protease inhibitors (serpins) is one of...

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Главные авторы: de Koning, Pieter J. A., Kummer, J. Alain, de Poot, Stefanie A. H., Quadir, Razi, Broekhuizen, Roel, McGettrick, Anne F., Higgins, Wayne J., Devreese, Bart, Worrall, D. Margaret, Bovenschen, Niels
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152296/
https://ncbi.nlm.nih.gov/pubmed/21857942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022645
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