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The Role of Serpinb9/Serine Protease Inhibitor 6 in Preventing Granzyme B—Dependent Hepatotoxicity

Virally infected hepatocytes are resistant to cytotoxic lymphocyte killing by perforin-dependent and granzyme-dependent effector mechanisms. The present studies were designed to examine the role of serine protease inhibitor 6 (SPI-6) in limiting granzyme B—dependent cytotoxic effector mechanisms in...

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Detalhes bibliográficos
Main Authors: Stout-Delgado, Heather W., Getachew, Yonas, Rogers, Thomas E., Miller, Bonnie C., Thiele, Dwain L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659535/
https://ncbi.nlm.nih.gov/pubmed/17685438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.21820
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