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All Human Granzymes Target hnRNP K That Is Essential for Tumor Cell Viability
Granule exocytosis by cytotoxic lymphocytes is the key mechanism to eliminate virus-infected cells and tumor cells. These lytic granules contain the pore-forming protein perforin and a set of five serine proteases called granzymes. All human granzymes display distinct substrate specificities and ind...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3391115/ https://ncbi.nlm.nih.gov/pubmed/22582387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365692 |
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