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Granzyme M targets host cell hnRNP K that is essential for human cytomegalovirus replication

Human cytomegalovirus (HCMV) is the most frequent viral cause of congenital defects and HCMV infection in immunocompromised patients may trigger devastating disease. Cytotoxic lymphocytes control HCMV by releasing granzymes towards virus-infected cells. In mice, granzyme M (GrM) has a physiological...

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Detalhes bibliográficos
Main Authors: van Domselaar, R, de Poot, S A H, Remmerswaal, E B M, Lai, K W, ten Berge, I J M, Bovenschen, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569982/
https://ncbi.nlm.nih.gov/pubmed/23099853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.132
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