Genetic Loci Modulate Macrophage Activity and Glomerular Damage in Experimental Glomerulonephritis

The Wistar Kyoto (WKY) rat is uniquely susceptible to experimentally induced crescentic glomerulonephritis. Two major quantitative trait loci (QTLs) on chromosomes 13 (Crgn1) and 16 (Crgn2) with logarithm of odds >8, as well as five other loci (Crgn3 through 7), largely explain this genetic susce...

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Autori principali: Behmoaras, Jacques, Smith, Jennifer, D'Souza, Zelpha, Bhangal, Gurjeet, Chawanasuntoropoj, Ratana, Tam, Frederick W.K., Pusey, Charles D., Aitman, Timothy J., Cook, H. Terence
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2010
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152224/
https://ncbi.nlm.nih.gov/pubmed/20488952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009090968
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