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Genetic Loci Modulate Macrophage Activity and Glomerular Damage in Experimental Glomerulonephritis
The Wistar Kyoto (WKY) rat is uniquely susceptible to experimentally induced crescentic glomerulonephritis. Two major quantitative trait loci (QTLs) on chromosomes 13 (Crgn1) and 16 (Crgn2) with logarithm of odds >8, as well as five other loci (Crgn3 through 7), largely explain this genetic susce...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Nephrology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152224/ https://ncbi.nlm.nih.gov/pubmed/20488952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009090968 |
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