Genetic Loci Modulate Macrophage Activity and Glomerular Damage in Experimental Glomerulonephritis

The Wistar Kyoto (WKY) rat is uniquely susceptible to experimentally induced crescentic glomerulonephritis. Two major quantitative trait loci (QTLs) on chromosomes 13 (Crgn1) and 16 (Crgn2) with logarithm of odds >8, as well as five other loci (Crgn3 through 7), largely explain this genetic susce...

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Bibliografski detalji
Glavni autori: Behmoaras, Jacques, Smith, Jennifer, D'Souza, Zelpha, Bhangal, Gurjeet, Chawanasuntoropoj, Ratana, Tam, Frederick W.K., Pusey, Charles D., Aitman, Timothy J., Cook, H. Terence
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2010
Teme:
Basic Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152224/
https://ncbi.nlm.nih.gov/pubmed/20488952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009090968
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