Characterisation of the macrophage transcriptome in glomerulonephritis-susceptible and -resistant rat strains

Crescentic glomerulonephritis (CRGN) is a major cause of rapidly progressive renal failure for which the underlying genetic basis is unknown. WKY rats show marked susceptibility to CRGN, while Lewis rats are resistant. Glomerular injury and crescent formation are macrophage-dependent and mainly expl...

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Bibliografiske detaljer
Main Authors: Maratou, Klio, Behmoaras, Jacques, Fewings, Chris, Srivastava, Prashant, D’Souza, Zelpha, Smith, Jennifer, Game, Laurence, Cook, Terence, Aitman, Tim
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048856/
https://ncbi.nlm.nih.gov/pubmed/21179115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2010.61
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