Characterisation of the macrophage transcriptome in glomerulonephritis-susceptible and -resistant rat strains

Crescentic glomerulonephritis (CRGN) is a major cause of rapidly progressive renal failure for which the underlying genetic basis is unknown. WKY rats show marked susceptibility to CRGN, while Lewis rats are resistant. Glomerular injury and crescent formation are macrophage-dependent and mainly expl...

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Detalhes bibliográficos
Main Authors: Maratou, Klio, Behmoaras, Jacques, Fewings, Chris, Srivastava, Prashant, D’Souza, Zelpha, Smith, Jennifer, Game, Laurence, Cook, Terence, Aitman, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048856/
https://ncbi.nlm.nih.gov/pubmed/21179115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2010.61
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