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Correlation of disease activity in proliferative glomerulonephritis with glomerular spleen tyrosine kinase expression

Spleen tyrosine kinase (SYK) is an important component of the intracellular signalling pathway for various immunoreceptors, and SYK inhibition has shown promise in preclinical models of autoimmune and glomerular disease. The description of SYK expression in human renal tissue, which would be desirab...

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Bibliografiska uppgifter
I publikationen:Kidney Int
Huvudupphovsmän: McAdoo, Stephen Paul, Bhangal, Gurjeet, Page, Theresa, Cook, Terence H, Pusey, Charles Dickson, Tam, Frederick Wai Keung
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488852/
https://ncbi.nlm.nih.gov/pubmed/25715120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.29
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