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The transcription factors STAT5A and STAT5B negatively regulate cell proliferation through the activation of Cdkn2b and Cdkn1a expression
Although the cytokine-inducible transcription factors STAT5 promote proliferation of a wide range of cell types, there are cell- and context specific cases in which loss of STAT5 results in enhanced cell proliferation. Here we report that loss of STAT5 from mouse embryonic fibroblasts (MEFs) leads t...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152209/ https://ncbi.nlm.nih.gov/pubmed/21038417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23882 |
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