Loss of Sexually Dimorphic Liver Gene Expression Upon Hepatocyte-specific Deletion of Stat5a-Stat5b Locus

Hepatocyte-specific, albumin-Cre recombinase-mediated deletion of the entire mouse Stat5a-Stat5b locus was carried out to evaluate the role of STAT5a and STAT5b (STAT5ab) in the sex-dependent transcriptional actions of GH in the liver. The resultant hepatocyte STAT5ab-deficient mice were fertile, an...

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Bibliographic Details
Main Authors: Holloway, Minita G., Cui, Yongzhi, Laz, Ekaterina, Hosui, Atsushi, Hennighausen, Lothar, Waxman, David J.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282149/
https://ncbi.nlm.nih.gov/pubmed/17317776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2006-1419
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