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The Tuberous Sclerosis Complex -mTOR Pathway Maintains the Quiescence and Survival of Naïve T Cells

Naïve T cells receive stimulation from the positive selecting ligand in the periphery for their survival. This stimulation does not normally lead to overt activation of T cells, as the T cells remain largely quiescent until they receive either antigenic or lymphopenic stimuli. The underlying mechani...

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Detalhes bibliográficos
Main Authors: Wu, Qi, Liu, Yu, Chen, Chong, Ikenoue, Tsuneo, Qiao, Yu, Li, Chi-Shan, Guan, Kun-Liang, Liu, Yang, Zheng, Pan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151493/
https://ncbi.nlm.nih.gov/pubmed/21709159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003968
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