Загрузка...

Peptide Ligands Incorporated into the Threefold Spike Capsid Domain to Re-Direct Gene Transduction of AAV8 and AAV9 In Vivo

Efficiency and specificity of viral vectors are vital issues in gene therapy. Insertion of peptide ligands into the adeno-associated viral (AAV) capsid at receptor binding sites can re-target AAV2-derived vectors to alternative cell types. Also, the use of serotypes AAV8 and -9 is more efficient tha...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Michelfelder, Stefan, Varadi, Karl, Raupp, Christina, Hunger, Agnes, Körbelin, Jakob, Pahrmann, Christiane, Schrepfer, Sonja, Müller, Oliver J., Kleinschmidt, Jürgen A., Trepel, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151269/
https://ncbi.nlm.nih.gov/pubmed/21850255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023101
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!