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Total Synthesis of Dolabelide C: A Phosphate-Mediated Approach
The first synthesis of dolabelide C (1), a cytotoxic marine macrolide, is reported utilizing a phosphate tether-mediated approach. Bicyclic phosphates (S,S,S(P))-5 and (R,R,R(P))-5 serve as the central building blocks for the construction of two major 1,3-anti-diol subunits in 1 through selective cl...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150593/ https://ncbi.nlm.nih.gov/pubmed/21528846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo2003506 |
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