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Phosphate Tether-Mediated Approach to the Formal Total Synthesis of (-)-Salicylihalamides A and B

[Image: see text] A concise formal synthesis of the cytotoxic macrolides (-)-salicylihalamides A and B is reported. Key features of the synthetic strategy include a chemoselective hydroboration, highly regio- and diastereoselective methyl cuprate addition, Pd-catalyzed formate reduction, and an E-se...

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Bibliografische gegevens
Hoofdauteurs: Chegondi, Rambabu, Tan, Mary M. L., Hanson, Paul R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271935/
https://ncbi.nlm.nih.gov/pubmed/21504150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo200337v
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