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Structure and stability of the lamin A tail domain and HGPS mutant
Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging syndrome caused by the expression and accumulation of a mutant form of lamin A, Δ50 lamin A. As a component of the cell's nucleoskeleton, lamin A plays an important role in the mechanical stabilization of the nuclear envelope and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150306/ https://ncbi.nlm.nih.gov/pubmed/21635954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2011.05.015 |
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