T4 RNA Ligase 2 truncated active site mutants: improved tools for RNA analysis

BACKGROUND: T4 RNA ligases 1 and 2 are useful tools for RNA analysis. Their use upstream of RNA analyses such as high-throughput RNA sequencing and microarrays has recently increased their importance. The truncated form of T4 RNA ligase 2, comprising amino acids 1-249 (T4 Rnl2tr), is an attractive t...

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Bibliographic Details
Main Authors: Viollet, Sebastien, Fuchs, Ryan T, Munafo, Daniela B, Zhuang, Fanglei, Robb, Gregory B
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149579/
https://ncbi.nlm.nih.gov/pubmed/21722378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-72
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