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Dynamical Basis for Drug Resistance of HIV-1 Protease

BACKGROUND: Protease inhibitors designed to bind to protease have become major anti-AIDS drugs. Unfortunately, the emergence of viral mutations severely limits the long-term efficiency of the inhibitors. The resistance mechanism of these diversely located mutations remains unclear. RESULTS: Here I u...

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Библиографические подробности
Главный автор: Mao, Yi
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149572/
https://ncbi.nlm.nih.gov/pubmed/21740562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-11-31
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