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Kinetics of Doubletime Kinase-dependent Degradation of the Drosophila Period Protein
Robust circadian oscillations of the proteins PERIOD (PER) and TIMELESS (TIM) are hallmarks of a functional clock in the fruit fly Drosophila melanogaster. Early morning phosphorylation of PER by the kinase Doubletime (DBT) and subsequent PER turnover is an essential step in the functioning of the D...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149356/ https://ncbi.nlm.nih.gov/pubmed/21659538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243618 |
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