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A DOUBLETIME Kinase Binding Domain on the Drosophila PERIOD Protein Is Essential for Its Hyperphosphorylation, Transcriptional Repression, and Circadian Clock Function

A common feature of animal circadian clocks is the progressive phosphorylation of PERIOD (PER) proteins from hypo- to hyperphosphorylated species, events that are highly dependent on casein kinase 1ɛ (termed DOUBLETIME [DBT] in Drosophila melanogaster) and necessary for normal clock progression. Dro...

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Bibliografiska uppgifter
Huvudupphovsmän: Kim, Eun Young, Ko, Hyuk Wan, Yu, Wangjie, Hardin, Paul E., Edery, Isaac
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951477/
https://ncbi.nlm.nih.gov/pubmed/17452449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02339-06
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