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A DOUBLETIME Kinase Binding Domain on the Drosophila PERIOD Protein Is Essential for Its Hyperphosphorylation, Transcriptional Repression, and Circadian Clock Function
A common feature of animal circadian clocks is the progressive phosphorylation of PERIOD (PER) proteins from hypo- to hyperphosphorylated species, events that are highly dependent on casein kinase 1ɛ (termed DOUBLETIME [DBT] in Drosophila melanogaster) and necessary for normal clock progression. Dro...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1951477/ https://ncbi.nlm.nih.gov/pubmed/17452449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02339-06 |
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