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A Role for the PERIOD:PERIOD Homodimer in the Drosophila Circadian Clock

Circadian clocks in eukaryotes rely on transcriptional feedback loops, in which clock genes repress their own transcription resulting in molecular oscillations with a period of ∼24 h. In Drosophila, the clock proteins Period (PER) and Timeless (TIM) operate in such a feedback loop, whereby they firs...

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Autors principals: Landskron, Johannes, Chen, Ko Fan, Wolf, Eva, Stanewsky, Ralf
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671555/
https://ncbi.nlm.nih.gov/pubmed/19402744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000003
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