γ-Secretase-regulated Proteolysis of the Notch Receptor by Mitochondrial Intermediate Peptidase

Notch is a transmembrane receptor that controls a diverse array of cellular processes including cell proliferation, differentiation, survival, and migration. The cellular outcome of Notch signaling is dependent on extracellular and intracellular signals, but the complexities of its regulation are no...

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Autores principales: Lee, Sheu-Fen, Srinivasan, Bhooma, Sephton, Chantelle F., Dries, Daniel R., Wang, Bing, Yu, Cong, Wang, Yun, Dewey, Colleen M., Shah, Sanjiv, Jiang, Jin, Yu, Gang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Enzymology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149338/
https://ncbi.nlm.nih.gov/pubmed/21685396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243154
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