Comparative Genomic Integration Profiling of Sleeping Beauty Transposons Mobilized With High Efficacy From Integrase-defective Lentiviral Vectors in Primary Human Cells

It has been previously shown that integrase-defective HIV-1-based gene vectors can serve, with moderate efficiency, as substrate for DNA transposition by a transiently expressed Sleeping Beauty (SB) transposase. Here, we describe the enhanced gene transfer properties of a HIV-1/SB hybrid vector that...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Moldt, Brian, Miskey, Csaba, Staunstrup, Nicklas Heine, Gogol-Döring, Andreas, Bak, Rasmus O, Sharma, Nynne, Mátés, Lajos, Izsvák, Zsuzsanna, Chen, Wei, Ivics, Zoltán, Mikkelsen, Jacob Giehm
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2011
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149173/
https://ncbi.nlm.nih.gov/pubmed/21468003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.47
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