Anti-CD22 Antibody Targeting of pH-responsive Micelles Enhances Small Interfering RNA Delivery and Gene Silencing in Lymphoma Cells

The application of small interfering RNA (siRNA) for cancer treatment is a promising strategy currently being explored in early phase clinical trials. However, efficient systemic delivery limits clinical implementation. We developed and tested a novel delivery system comprised of (i) an internalizin...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Palanca-Wessels, Maria C, Convertine, Anthony J, Cutler-Strom, Richelle, Booth, Garrett C, Lee, Fan, Berguig, Geoffrey Y, Stayton, Patrick S, Press, Oliver W
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2011
Предметы:
Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149160/
https://ncbi.nlm.nih.gov/pubmed/21629223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.104
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы