Self-complementary AAV2.5-BMP2-coated Femoral Allografts Mediated Superior Bone Healing Versus Live Autografts in Mice With Equivalent Biomechanics to Unfractured Femur

Structural allografts used for critical bone defects have limited osteogenic properties for biointegration. Although ex vivo tissue-engineered constructs expressing bone morphogenetic protein-2 (BMP2) have demonstrated efficacy in critical defect models, similar success has not been achieved with of...

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Autors principals: Yazici, Cemal, Takahata, Masahiko, Reynolds, David G, Xie, Chao, Samulski, R Jude, Samulski, Jade, Beecham, E Jeffrey, Gertzman, Arthur A, Spilker, Mark, Zhang, Xinping, O'Keefe, Regis J, Awad, Hani A, Schwarz, Edward M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149158/
https://ncbi.nlm.nih.gov/pubmed/21206485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.294
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