Self-complementary AAV2.5-BMP2-coated Femoral Allografts Mediated Superior Bone Healing Versus Live Autografts in Mice With Equivalent Biomechanics to Unfractured Femur

Structural allografts used for critical bone defects have limited osteogenic properties for biointegration. Although ex vivo tissue-engineered constructs expressing bone morphogenetic protein-2 (BMP2) have demonstrated efficacy in critical defect models, similar success has not been achieved with of...

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Autores principales: Yazici, Cemal, Takahata, Masahiko, Reynolds, David G, Xie, Chao, Samulski, R Jude, Samulski, Jade, Beecham, E Jeffrey, Gertzman, Arthur A, Spilker, Mark, Zhang, Xinping, O'Keefe, Regis J, Awad, Hani A, Schwarz, Edward M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2011
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149158/
https://ncbi.nlm.nih.gov/pubmed/21206485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.294
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